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UniNest

NEET ]1[ Contd...

NEET Biology - Excretory Products and their Elimination

Duration: 150 minutesTotal Marks: 600Questions: 150Negative Marking: -1

Instructions:

  1. Each question has four options (1), (2), (3), (4). Choose the most correct answer.
  2. Each correct answer carries 4 marks.
  3. Each wrong answer will deduct 1 marks.
  4. Unanswered questions will not be penalised.
1.Which set contains only the major nitrogenous wastes mentioned in the chapter?
(1)Ammonia, urea and uric acid
(2)Ammonia, carbon dioxide and sulphate
(3)Urea, chloride and phosphate
(4)Uric acid, water and potassium ions
2.Choose the correct toxicity–water requirement relationship.
(1)Ammonia: least toxic, minimum water; uric acid: most toxic, large water
(2)Ammonia: most toxic, large water; uric acid: least toxic, minimum water
(3)Urea: most toxic, no water; uric acid: moderately toxic, large water
(4)Ammonia and uric acid both require equal water because both are nitrogenous wastes
3.The term ammonotelism refers to the excretion of:
(1)Urea
(2)Uric acid
(3)Ammonia
(4)Ammonium phosphate
4.Which group is correctly placed under ammonotelic animals as per the chapter?
(1)Mammals, birds and insects
(2)Many bony fishes, aquatic amphibians and aquatic insects
(3)Reptiles, land snails and marine mammals
(4)Marine fishes, birds and terrestrial amphibians
5.Ammonia is generally eliminated from ammonotelic animals by:
(1)conversion in kidney matrix and excretion as pellets
(2)diffusion across body or gill surfaces as ammonium ions
(3)filtration as plasma proteins through Bowman's capsule
(4)storage in renal pelvis and release through ureters
6.Which statement is accurate for ureotelic animals according to the chapter?
(1)Reptiles and birds are mainly ureotelic because they excrete pellets.
(2)Mammals, many terrestrial amphibians and marine fishes mainly excrete urea.
(3)Bony fishes and aquatic insects are mainly ureotelic in nature.
(4)Ureotelic animals convert uric acid into ammonia in kidney tubules.
7.In ureotelic animals, ammonia produced by metabolism is first converted into urea mainly in the:
(1)kidney tubule
(2)liver
(3)renal pelvis
(4)urinary bladder
8.Which combination is correct for uricotelic animals?
(1)Reptiles, birds, land snails and insects — uric acid as pellet or paste
(2)Mammals, marine fishes and terrestrial amphibians — uric acid in dissolved form
(3)Bony fishes, aquatic amphibians and aquatic insects — uric acid as ammonium ions
(4)Crustaceans, rotifers and Amphioxus — urea retained in kidney matrix
9.Which animal-excretory structure pair is correctly matched?
(1)Planaria — green glands
(2)Cockroach — Malpighian tubules
(3)Prawn — nephridia
(4)Earthworm — protonephridia only
10.Protonephridia are primarily concerned with:
(1)respiration and circulation
(2)ionic and fluid volume regulation
(3)secretion of bile pigments
(4)formation of renal columns
11.The human excretory system does NOT include a pair of:
(1)kidneys
(2)ureters
(3)urinary bladders
(4)renal arteries
12.The hilum of kidney is best described as:
(1)a conical mass projecting into calyces
(2)a notch on the inner concave surface through which ureter, blood vessels and nerves enter
(3)the outer tough covering of kidney
(4)the straight tube into which DCTs open
13.Columns of Bertini are:
(1)extensions of cortex between medullary pyramids
(2)branches of renal artery entering glomerulus
(3)modified DCT cells in contact with afferent arteriole
(4)projections of renal pelvis inside hilum
14.Nearly how many nephrons are present in each human kidney?
(1)One thousand
(2)One lakh
(3)One million
(4)Ten million
15.Each nephron has two main parts:
(1)renal pelvis and calyces
(2)glomerulus and renal tubule
(3)cortex and medulla
(4)ureter and urinary bladder
16.The glomerulus is formed by the:
(1)efferent arteriole and drained by afferent arteriole
(2)afferent arteriole and drained by efferent arteriole
(3)renal vein and drained by renal artery
(4)vasa recta and drained by collecting duct
17.Malpighian body or renal corpuscle consists of:
(1)PCT and DCT
(2)glomerulus and Bowman's capsule
(3)Henle's loop and collecting duct
(4)renal pelvis and calyces
18.Which sequence correctly follows the renal tubule pathway?
(1)Bowman's capsule → PCT → Henle's loop → DCT → collecting duct
(2)DCT → Henle's loop → PCT → Bowman's capsule → collecting duct
(3)PCT → Bowman's capsule → DCT → Henle's loop → ureter
(4)Collecting duct → DCT → PCT → Henle's loop → Bowman's capsule
19.Cortical nephrons are characterized by:
(1)very long loops deep into medulla and abundant vasa recta
(2)short loops extending very little into medulla and absent or reduced vasa recta
(3)no glomerulus but large renal pelvis
(4)medullary corpuscle and cortical loop of Henle
20.The vasa recta is formed as a U-shaped vessel running parallel to:
(1)collecting duct
(2)Henle's loop
(3)renal pelvis
(4)ureter
21.The three main processes of urine formation are:
(1)filtration, reabsorption and secretion
(2)digestion, absorption and assimilation
(3)micturition, vasodilation and dialysis
(4)osmosis, coagulation and bile secretion
22.The filtration barrier in glomerular filtration includes all EXCEPT:
(1)endothelium of glomerular blood vessels
(2)epithelium of Bowman's capsule
(3)basement membrane
(4)wall of collecting duct
23.Podocytes are associated with:
(1)forming filtration slits in Bowman's capsule epithelium
(2)secreting bile pigments from liver
(3)forming calyces around the renal pelvis
(4)converting angiotensinogen into angiotensin II
24.Glomerular filtrate is considered protein-free mainly because:
(1)proteins are converted into urea before filtration
(2)almost all plasma constituents except proteins pass into Bowman's capsule
(3)proteins are actively secreted into collecting duct
(4)proteins are removed by green glands
25.A healthy adult's GFR is approximately:
(1)12.5 ml/min and 18 L/day
(2)125 ml/min and 180 L/day
(3)1.5 ml/min and 1.5 L/day
(4)1200 ml/min and 125 L/day
26.JGA is formed by cellular modifications in the:
(1)PCT and efferent arteriole
(2)DCT and afferent arteriole
(3)collecting duct and renal vein
(4)Bowman's capsule and vasa recta
27.A fall in GFR activates JG cells to release:
(1)ADH
(2)ANF
(3)renin
(4)anti-heparin
28.Nearly what percentage of filtrate is reabsorbed by renal tubules?
(1)50%
(2)70–80%
(3)90%
(4)99%
29.Which substances are actively reabsorbed from the filtrate as per the chapter?
(1)glucose, amino acids and Na+
(2)urea, ammonia and ketone bodies
(3)H+, K+ and NH3
(4)bilirubin, biliverdin and sterols
30.Tubular secretion is important because it helps maintain:
(1)only blood glucose concentration
(2)ionic and acid-base balance
(3)body temperature only
(4)bile pigment composition
31.Identify the correct statements about nitrogenous wastes.
A. Ammonia requires large water for elimination.
B. Uric acid is least toxic among the major nitrogenous wastes.
C. Urea is excreted as pellet or paste by reptiles and birds.
D. Ammonia is generally excreted as ammonium ions by diffusion.
(1)A, B and D only
(2)A and C only
(3)B, C and D only
(4)A, B, C and D
32.Choose the correct statements about ureotelism.
A. It is found in mammals.
B. Many terrestrial amphibians are included.
C. Marine fishes mainly excrete urea according to the chapter.
D. Ammonia is converted into urea in kidneys before entering blood.
(1)A and B only
(2)A, B and C only
(3)B, C and D only
(4)A, C and D only
33.Which statements about ammonotelic elimination are correct?
A. Ammonia is readily soluble.
B. It is generally excreted through gill surfaces in fish.
C. Kidneys play the major role in ammonia removal.
D. It may diffuse across body surfaces.
(1)A, B and D only
(2)A and C only
(3)B and C only
(4)A, B, C and D
34.Select the correct statements about excretory structures.
A. Flame cells occur in Planaria.
B. Green glands occur in prawns.
C. Malpighian tubules occur in cockroaches.
D. Nephridia are the excretory structures of most insects.
(1)A, B and C only
(2)A and D only
(3)B, C and D only
(4)A, B, C and D
35.Identify the correct statements about protonephridia.
A. They are also called flame cells.
B. They are found in Platyhelminthes and Amphioxus.
C. Their primary concern is bile excretion.
D. They are involved in osmoregulation.
(1)A, B and D only
(2)A and C only
(3)B and C only
(4)A, B, C and D
36.Which of the following statements about kidney anatomy are correct?
A. The outer zone is cortex.
B. The inner zone is medulla.
C. Medullary pyramids project into calyces.
D. Renal columns are extensions of medulla between cortical pyramids.
(1)A, B and C only
(2)A and D only
(3)B, C and D only
(4)A, B, C and D
37.Choose the correct statements about hilum and renal pelvis.
A. Hilum is on the inner concave surface.
B. Ureter, blood vessels and nerves enter through hilum.
C. Renal pelvis lies inner to hilum.
D. Calyces are projections of renal columns.
(1)A, B and C only
(2)A and D only
(3)B and C only
(4)A, B, C and D
38.Which statements about nephron structure are correct?
A. The renal tubule begins with Bowman's capsule.
B. Bowman's capsule encloses glomerulus.
C. Glomerulus and Bowman's capsule form renal corpuscle.
D. PCT directly opens into renal pelvis without DCT.
(1)A, B and C only
(2)A and D only
(3)B, C and D only
(4)A, B, C and D
39.Regarding nephron location, which statements are correct?
A. Malpighian corpuscle is in cortex.
B. PCT and DCT are cortical.
C. Loop of Henle dips into medulla.
D. Collecting duct is the first part of the renal tubule.
(1)A, B and C only
(2)A and D only
(3)B and D only
(4)A, B, C and D
40.Which statements about cortical and juxtamedullary nephrons are correct?
A. Cortical nephrons have short loops.
B. Juxtamedullary nephrons have long loops deep into medulla.
C. Vasa recta is absent or reduced in cortical nephrons.
D. Cortical nephrons lack glomeruli.
(1)A, B and C only
(2)A and D only
(3)B, C and D only
(4)A, B, C and D
41.Which statements correctly describe glomerular filtration?
A. It is the first step in urine formation.
B. It is caused by glomerular capillary blood pressure.
C. It occurs through three layers.
D. It allows plasma proteins to freely enter the Bowman's capsule lumen.
(1)A, B and C only
(2)A and D only
(3)B, C and D only
(4)A, B, C and D
42.Select correct statements about GFR and its regulation.
A. GFR means filtrate formed per minute.
B. Healthy GFR is about 125 ml/min.
C. JGA helps regulate GFR.
D. Fall in GFR suppresses renin release from JG cells.
(1)A, B and C only
(2)A and D only
(3)B, C and D only
(4)A, B, C and D
43.Which statements about reabsorption are correct?
A. About 99% filtrate is reabsorbed.
B. Glucose and amino acids are actively reabsorbed.
C. Water reabsorption in initial segments is passive.
D. Nitrogenous wastes are actively reabsorbed as the main useful nutrients.
(1)A, B and C only
(2)A and D only
(3)B and C only
(4)A, B, C and D
44.Choose the correct statements about PCT.
A. It has simple cuboidal brush-border epithelium.
B. Brush border increases surface area.
C. It reabsorbs nearly all essential nutrients.
D. It is the site of minimum reabsorption in nephron.
(1)A, B and C only
(2)A and D only
(3)B and D only
(4)A, B, C and D
45.Which statements about Henle's loop are correct?
A. Descending limb is permeable to water.
B. Descending limb is almost impermeable to electrolytes.
C. Ascending limb is impermeable to water.
D. Ascending limb concentrates the filtrate as it moves upward.
(1)A, B and C only
(2)A and D only
(3)B, C and D only
(4)A, B, C and D
46.Select the correct statements about DCT.
A. Na+ and water reabsorption is conditional.
B. HCO3- can be reabsorbed.
C. H+, K+ and NH3 can be secreted.
D. DCT primarily secretes bile pigments into urine.
(1)A, B and C only
(2)A and D only
(3)B and C only
(4)A, B, C and D
47.Which statements about collecting duct are correct?
A. It extends from cortex to inner medulla.
B. Large water reabsorption here can produce concentrated urine.
C. It allows small urea passage into medullary interstitium.
D. It never participates in pH regulation.
(1)A, B and C only
(2)A and D only
(3)B, C and D only
(4)A, B, C and D
48.Identify the correct statements about the countercurrent mechanism.
A. Henle's loop has opposite filtrate flow in its two limbs.
B. Vasa recta has opposite blood flow in its two limbs.
C. Proximity of Henle's loop and vasa recta helps maintain medullary gradient.
D. The gradient decreases from inner medulla to cortex according to the stated values.
(1)A, B and C only
(2)A and D only
(3)B and D only
(4)A, B, C and D
49.Which statements about medullary osmolarity are correct?
A. It rises from about 300 mOsmol/L in cortex to 1200 mOsmol/L in inner medulla.
B. It is mainly due to NaCl and urea.
C. It helps water leave the collecting tubule.
D. It is maintained mainly by bilirubin and cholesterol.
(1)A, B and C only
(2)A and D only
(3)B, C and D only
(4)A, B, C and D
50.Select the correct statements about NaCl and urea in the countercurrent mechanism.
A. NaCl is transported by ascending limb of Henle's loop.
B. NaCl exchanges with descending limb of vasa recta.
C. NaCl returns to interstitium through ascending vasa recta.
D. Urea enters the thin descending limb and leaves through Bowman's capsule.
(1)A, B and C only
(2)A and D only
(3)B and C only
(4)A, B, C and D
51.Which statements about ADH are correct?
A. It is also called vasopressin.
B. It is released from neurohypophysis under hypothalamic stimulation.
C. It facilitates water reabsorption from latter tubule parts.
D. It promotes diuresis by blocking water reabsorption.
(1)A, B and C only
(2)A and D only
(3)B, C and D only
(4)A, B, C and D
52.Choose the correct statements about osmoreceptor feedback.
A. Excessive fluid loss activates osmoreceptors.
B. Increased body-fluid volume suppresses ADH release.
C. Osmoreceptors respond to ionic concentration changes.
D. Osmoreceptors are activated only by urea concentration in dialysing fluid.
(1)A, B and C only
(2)A and D only
(3)B and C only
(4)A, B, C and D
53.Identify the correct RAAS sequence.
(1)Fall in GFR → renin → angiotensinogen → angiotensin I → angiotensin II → aldosterone
(2)Rise in GFR → aldosterone → renin → ANF → angiotensin II
(3)Fall in GFR → ANF → vasodilation → aldosterone suppression only
(4)Fluid excess → ADH → renin → anti-heparin → uremia
54.Which statements about angiotensin II and aldosterone are correct?
A. Angiotensin II is a powerful vasoconstrictor.
B. Angiotensin II increases glomerular blood pressure and GFR.
C. Aldosterone promotes Na+ and water reabsorption from distal tubules.
D. Aldosterone decreases blood pressure and GFR.
(1)A, B and C only
(2)A and D only
(3)B, C and D only
(4)A, B, C and D
55.Which statements about ANF are correct?
A. It is released when blood flow to atria increases.
B. It causes vasodilation.
C. It decreases blood pressure.
D. It acts as a check on the renin-angiotensin mechanism by causing vasoconstriction.
(1)A, B and C only
(2)A and D only
(3)B, C and D only
(4)A, B, C and D
56.Which statements correctly describe micturition?
A. It involves voluntary CNS signal after bladder storage.
B. Stretch receptors on bladder walls send signals to CNS.
C. Motor messages contract bladder smooth muscles.
D. Urethral sphincter contracts simultaneously to release urine.
(1)A, B and C only
(2)A and D only
(3)B and C only
(4)A, B, C and D
57.Choose the correct statements about normal urine.
A. Adult daily volume is 1 to 1.5 L.
B. It is slightly acidic with pH about 6.0.
C. Urea excretion averages 25–30 g/day.
D. Its characteristic colour is dark green due to biliverdin.
(1)A, B and C only
(2)A and D only
(3)B and D only
(4)A, B, C and D
58.Which statements about clinical urine findings are correct?
A. Glycosuria means glucose in urine.
B. Ketonuria means ketone bodies in urine.
C. Both may indicate diabetes mellitus.
D. Glycosuria means urea accumulation in blood.
(1)A, B and C only
(2)A and D only
(3)B and C only
(4)A, B, C and D
59.Select correct statements about lungs and liver in excretion.
A. Lungs remove CO2 about 200 mL/min.
B. Lungs also eliminate significant water daily.
C. Liver secretes bile with bilirubin and biliverdin.
D. Liver removes wastes only through urine.
(1)A, B and C only
(2)A and D only
(3)B, C and D only
(4)A, B, C and D
60.Which statements about skin secretions are correct?
A. Sweat contains NaCl, small urea and lactic acid.
B. Primary function of sweat is cooling.
C. Sebum provides a protective oily covering.
D. Sebum mainly contains glucose and amino acids.
(1)A, B and C only
(2)A and D only
(3)B and D only
(4)A, B, C and D
61.Identify correct statements about uremia and hemodialysis.
A. Uremia is accumulation of urea in blood.
B. Uremia can be highly harmful.
C. Hemodialysis can remove urea in such patients.
D. Hemodialysis is used because nitrogenous wastes are higher in dialysing fluid than in blood.
(1)A, B and C only
(2)A and D only
(3)B and C only
(4)A, B, C and D
62.Which statements about the dialysis unit are correct?
A. It contains a coiled cellophane tube.
B. It is surrounded by dialysing fluid.
C. Dialysing fluid resembles plasma but lacks nitrogenous wastes.
D. Molecule movement across the membrane is independent of concentration gradient.
(1)A, B and C only
(2)A and D only
(3)B, C and D only
(4)A, B, C and D
63.Which statements about hemodialysis sequence are correct?
A. Blood is drained from a convenient artery.
B. Heparin is added before blood enters the unit.
C. Cleared blood returns through a vein after anti-heparin.
D. The first step is addition of anti-heparin before arterial drainage.
(1)A, B and C only
(2)A and D only
(3)B and D only
(4)A, B, C and D
64.Choose the correct statements about renal disorders.
A. Renal calculi are stones or insoluble masses of crystallised salts.
B. Oxalates are an example mentioned with renal calculi.
C. Glomerulonephritis is inflammation of glomeruli.
D. Uremia means ketone bodies in urine.
(1)A, B and C only
(2)A and D only
(3)B, C and D only
(4)A, B, C and D
65.Which of the following is INCORRECT about uric acid excretion?
(1)It minimizes water loss.
(2)It is least toxic among major nitrogenous wastes.
(3)It is excreted as pellet or paste in uricotelic animals.
(4)It is the main waste of many bony fishes and aquatic amphibians.
66.Select the wrongly matched pair.
(1)Nephridia — earthworms
(2)Green glands — prawns
(3)Malpighian tubules — cockroaches
(4)Flame cells — mammals
67.Which statement is NOT true about human kidney structure?
(1)The outer kidney layer is a tough capsule.
(2)The kidney has an outer cortex and inner medulla.
(3)Medullary pyramids project into calyces.
(4)Renal pelvis is the outer tough covering of kidney.
68.Which statement is INCORRECT?
(1)Bowman's capsule is double-walled and cup-like.
(2)Glomerulus is a tuft of capillaries.
(3)Efferent arteriole forms the glomerular capillary tuft.
(4)Afferent arteriole is a branch of renal artery.
69.Which of the following is NOT a cortical part of the nephron according to the chapter?
(1)Malpighian corpuscle
(2)PCT
(3)DCT
(4)Deep loop of Henle
70.Which option is NOT correctly associated with glomerular filtration?
(1)Blood pressure is the driving force.
(2)Endothelium is one filtration layer.
(3)Plasma proteins pass freely into Bowman's capsule.
(4)Podocytes form filtration slits.
71.Which statement is INCORRECT about GFR?
(1)It is filtrate formed by kidneys per minute.
(2)It is about 125 ml/min in a healthy person.
(3)It equals approximately 180 L/day.
(4)It is normally 1.5 L/day because that is urine output.
72.Which of the following is NOT actively reabsorbed in the example list given in the chapter?
(1)glucose
(2)amino acids
(3)Na+
(4)nitrogenous wastes
73.Which is NOT secreted into filtrate by tubular cells during urine formation as listed?
(1)H+
(2)K+
(3)ammonia
(4)glucose
74.Which statement is wrong for PCT?
(1)It has simple cuboidal brush-border epithelium.
(2)It reabsorbs nearly all essential nutrients.
(3)It secretes H+ and ammonia.
(4)It is the region where reabsorption is minimum.
75.Which statement is NOT true about the descending limb of Henle's loop?
(1)It is permeable to water.
(2)It is almost impermeable to electrolytes.
(3)It concentrates the filtrate while moving down.
(4)It is impermeable to water and transports electrolytes upward.
76.Which statement is INCORRECT about ascending limb of Henle's loop?
(1)It is impermeable to water.
(2)It allows electrolyte transport.
(3)It dilutes filtrate as filtrate moves upward.
(4)It is the main site of large water reabsorption to form concentrated urine.
77.Which of the following does NOT belong to DCT function as described?
(1)conditional reabsorption of Na+
(2)conditional reabsorption of water
(3)selective secretion of H+, K+ and NH3
(4)transport of NaCl to descending vasa recta
78.Which is NOT a contributor or participant explicitly stated for the medullary concentration mechanism?
(1)Henle's loop
(2)vasa recta
(3)NaCl and urea
(4)green glands
79.Which statement contradicts the chapter's osmolarity gradient?
(1)Cortex: about 300 mOsmol/L
(2)Inner medulla: about 1200 mOsmol/L
(3)Gradient increases toward inner medulla
(4)Gradient is mainly caused by glucose and amino acids
80.Which of the following is NOT a correct ADH statement?
(1)ADH is also vasopressin.
(2)ADH is released from neurohypophysis.
(3)ADH facilitates water reabsorption from latter tubule parts.
(4)ADH promotes water elimination to make urine hypotonic.
81.Which event does NOT activate renin release according to the chapter?
(1)Fall in glomerular blood flow
(2)Fall in glomerular blood pressure
(3)Fall in GFR
(4)Increase in blood flow to atria
82.Which is NOT an effect of ANF?
(1)vasodilation
(2)decrease in blood pressure
(3)checking renin-angiotensin mechanism
(4)increase in glomerular blood pressure by powerful vasoconstriction
83.Which statement is INCORRECT about micturition?
(1)Urinary bladder stores urine until CNS signal.
(2)Bladder stretch initiates signalling.
(3)CNS causes bladder muscle contraction.
(4)Urethral sphincter contracts to release urine.
84.Which urine feature is NOT stated for normal adult urine in the chapter?
(1)light yellow colour
(2)slightly acidic pH around 6.0
(3)average 1–1.5 L/day
(4)strongly alkaline pH around 9.0
85.Which is NOT part of bile-containing substances listed for liver excretion?
(1)bilirubin
(2)biliverdin
(3)cholesterol
(4)renin
86.Which is NOT stated as a component or role of sweat?
(1)NaCl
(2)small amounts of urea
(3)lactic acid
(4)primary excretion of all nitrogenous wastes
87.Which of the following is NOT correctly matched?
(1)Uremia — urea accumulation in blood
(2)Renal calculi — crystallised salt masses in kidney
(3)Glomerulonephritis — inflammation of glomeruli
(4)Glycosuria — ketone bodies in urine
88.Match List-I with List-II.
List-I: A. Ammonotelic B. Ureotelic C. Uricotelic D. Green glands
List-II: i. Prawns ii. Reptiles/birds iii. Mammals iv. Many bony fishes
(1)A-iv, B-iii, C-ii, D-i
(2)A-iii, B-iv, C-i, D-ii
(3)A-ii, B-iii, C-iv, D-i
(4)A-iv, B-i, C-ii, D-iii
89.Match the excretory structures with their examples.
A. Protonephridia B. Nephridia C. Malpighian tubules D. Antennal glands
i. Cockroach ii. Prawn iii. Earthworm iv. Planaria
(1)A-iv, B-iii, C-i, D-ii
(2)A-iii, B-iv, C-ii, D-i
(3)A-i, B-ii, C-iii, D-iv
(4)A-iv, B-i, C-iii, D-ii
90.Match kidney structures with descriptions.
A. Hilum B. Renal pelvis C. Capsule D. Columns of Bertini
i. tough outer layer ii. cortical extensions between pyramids iii. notch for ureter/vessels/nerves iv. funnel-shaped space with calyces
(1)A-iii, B-iv, C-i, D-ii
(2)A-iv, B-iii, C-i, D-ii
(3)A-iii, B-ii, C-iv, D-i
(4)A-i, B-iv, C-iii, D-ii
91.Match nephron structures with descriptions.
A. Glomerulus B. Bowman's capsule C. Renal corpuscle D. Vasa recta
i. U-shaped vessel parallel to Henle's loop ii. tuft of capillaries iii. double-walled cup iv. glomerulus plus Bowman's capsule
(1)A-ii, B-iii, C-iv, D-i
(2)A-iii, B-ii, C-i, D-iv
(3)A-ii, B-i, C-iii, D-iv
(4)A-iv, B-iii, C-ii, D-i
92.Match nephron segments with major features.
A. PCT B. Descending limb C. Ascending limb D. DCT
i. conditional Na+ and water reabsorption ii. brush-border epithelium iii. water permeable, electrolytes nearly impermeable iv. water impermeable, electrolyte transport
(1)A-ii, B-iii, C-iv, D-i
(2)A-i, B-iii, C-iv, D-ii
(3)A-ii, B-iv, C-iii, D-i
(4)A-iii, B-ii, C-i, D-iv
93.Match substances with their renal handling in the chapter.
A. Glucose B. H+ C. Urea in collecting duct D. Proteins in filtration
i. generally excluded from filtrate ii. actively reabsorbed iii. secreted into filtrate iv. small amount enters medullary interstitium
(1)A-ii, B-iii, C-iv, D-i
(2)A-iii, B-ii, C-i, D-iv
(3)A-ii, B-iv, C-iii, D-i
(4)A-i, B-iii, C-iv, D-ii
94.Match regulatory factors with effects.
A. ADH B. Renin C. Angiotensin II D. ANF
i. vasodilation/decreased BP ii. water reabsorption from latter tubule iii. converts angiotensinogen toward angiotensin I iv. powerful vasoconstrictor
(1)A-ii, B-iii, C-iv, D-i
(2)A-i, B-iii, C-iv, D-ii
(3)A-ii, B-iv, C-iii, D-i
(4)A-iv, B-iii, C-ii, D-i
95.Match triggers with responses.
A. Fluid loss B. Fall in GFR C. Increased atrial blood flow D. Bladder stretch
i. micturition signalling ii. ADH release iii. renin release iv. ANF release
(1)A-ii, B-iii, C-iv, D-i
(2)A-iii, B-ii, C-iv, D-i
(3)A-ii, B-iv, C-iii, D-i
(4)A-i, B-iii, C-iv, D-ii
96.Match clinical terms with meanings.
A. Glycosuria B. Ketonuria C. Uremia D. Glomerulonephritis
i. urea in blood ii. inflammation of glomeruli iii. ketone bodies in urine iv. glucose in urine
(1)A-iv, B-iii, C-i, D-ii
(2)A-iii, B-iv, C-i, D-ii
(3)A-iv, B-i, C-iii, D-ii
(4)A-i, B-iii, C-iv, D-ii
97.Match other excretory organs with eliminated substances/features.
A. Lungs B. Liver C. Sweat glands D. Sebaceous glands
i. sebum with sterols/hydrocarbons/waxes ii. CO2 and water iii. bile pigments/drugs etc. iv. NaCl, urea, lactic acid
(1)A-ii, B-iii, C-iv, D-i
(2)A-iii, B-ii, C-i, D-iv
(3)A-ii, B-iv, C-iii, D-i
(4)A-i, B-iii, C-iv, D-ii
98.Match hemodialysis items with roles.
A. Heparin B. Cellophane tube C. Dialysing fluid D. Anti-heparin
i. added before blood returns ii. lacks nitrogenous wastes iii. porous membrane route iv. anticoagulant added before dialysis
(1)A-iv, B-iii, C-ii, D-i
(2)A-i, B-iii, C-ii, D-iv
(3)A-iv, B-ii, C-iii, D-i
(4)A-iii, B-iv, C-ii, D-i
99.Match waste type with water strategy.
A. Ammonia B. Uric acid C. Urea D. Terrestrial adaptation
i. less toxic waste for conservation ii. most toxic, needs large water iii. least toxic, minimum water loss iv. formed in liver from ammonia in ureotelic animals
(1)A-ii, B-iii, C-iv, D-i
(2)A-iii, B-ii, C-iv, D-i
(3)A-ii, B-i, C-iii, D-iv
(4)A-iv, B-iii, C-ii, D-i
100.Match values with descriptions.
A. 1100–1200 ml/min B. 125 ml/min C. 180 L/day D. 1–1.5 L/day
i. average urine excreted ii. blood filtered by kidneys per minute iii. GFR per minute iv. filtrate per day
(1)A-ii, B-iii, C-iv, D-i
(2)A-iii, B-ii, C-i, D-iv
(3)A-ii, B-iv, C-iii, D-i
(4)A-i, B-iii, C-iv, D-ii
101.Match osmolarity/quantity values.
A. 300 mOsmol/L B. 1200 mOsmol/L C. four times D. 25–30 g/day
i. urea excreted ii. inner medulla osmolarity iii. cortex osmolarity iv. urine concentration relative to initial filtrate
(1)A-iii, B-ii, C-iv, D-i
(2)A-ii, B-iii, C-iv, D-i
(3)A-iii, B-i, C-iv, D-ii
(4)A-iv, B-ii, C-iii, D-i
102.Match nephron types/features.
A. Cortical nephron B. Juxtamedullary nephron C. Vasa recta D. Peritubular capillaries
i. long loop deep into medulla ii. short loop, little medulla iii. formed from efferent arteriole around tubule iv. U-shaped vessel parallel to Henle's loop
(1)A-ii, B-i, C-iv, D-iii
(2)A-i, B-ii, C-iv, D-iii
(3)A-ii, B-iii, C-iv, D-i
(4)A-iv, B-i, C-ii, D-iii
103.Match nephron segment with pH/ion role.
A. PCT B. DCT C. Collecting duct D. Tubular secretion in general
i. H+ and K+ secretion helps pH/ionic balance ii. H+ and ammonia secretion plus HCO3- absorption iii. HCO3- reabsorption and H+/K+/NH3 secretion iv. maintains ionic and acid-base balance
(1)A-ii, B-iii, C-i, D-iv
(2)A-iii, B-ii, C-i, D-iv
(3)A-ii, B-i, C-iii, D-iv
(4)A-iv, B-iii, C-i, D-ii
104.Match processes with descriptions.
A. Glomerular filtration B. Reabsorption C. Secretion D. Micturition
i. H+/K+/ammonia into filtrate ii. release of urine iii. first step by glomerulus iv. movement of useful substances/water back to blood
(1)A-iii, B-iv, C-i, D-ii
(2)A-iv, B-iii, C-i, D-ii
(3)A-iii, B-i, C-iv, D-ii
(4)A-ii, B-iv, C-i, D-iii
105.Match diagram figures with main idea based on captions/content.
A. Fig. 16.1 B. Fig. 16.2 C. Fig. 16.3 D. Fig. 16.4
i. Malpighian body ii. Human urinary system iii. L.S. kidney iv. nephron with blood vessels/duct/tubule
(1)A-ii, B-iii, C-iv, D-i
(2)A-iii, B-ii, C-iv, D-i
(3)A-ii, B-i, C-iv, D-iii
(4)A-iv, B-iii, C-ii, D-i
106.Assertion A: Ammonotelic animals generally require availability of water for nitrogenous waste elimination.
Reason R: Ammonia is the most toxic major nitrogenous waste and requires a large amount of water for elimination.
(1)Both A and R are true and R is the correct explanation of A.
(2)Both A and R are true but R is not the correct explanation of A.
(3)A is true but R is false.
(4)A is false but R is true.
107.Assertion A: Kidneys play the main role in removing ammonia in ammonotelic fishes.
Reason R: Ammonia is generally excreted by diffusion across gill surfaces as ammonium ions.
(1)Both A and R are true and R is the correct explanation of A.
(2)Both A and R are true but R is not the correct explanation of A.
(3)A is true but R is false.
(4)A is false but R is true.
108.Assertion A: Terrestrial animals are generally ureotelic or uricotelic rather than ammonotelic.
Reason R: Terrestrial adaptation required production of less toxic wastes for conserving water.
(1)Both A and R are true and R is the correct explanation of A.
(2)Both A and R are true but R is not the correct explanation of A.
(3)A is true but R is false.
(4)A is false but R is true.
109.Assertion A: Protonephridia are primarily osmoregulatory.
Reason R: They are concerned with ionic and fluid volume regulation.
(1)Both A and R are true and R is the correct explanation of A.
(2)Both A and R are true but R is not the correct explanation of A.
(3)A is true but R is false.
(4)A is false but R is true.
110.Assertion A: Glomerular filtration is considered ultrafiltration.
Reason R: Almost all plasma constituents except proteins pass into Bowman's capsule.
(1)Both A and R are true and R is the correct explanation of A.
(2)Both A and R are true but R is not the correct explanation of A.
(3)A is true but R is false.
(4)A is false but R is true.
111.Assertion A: A fall in GFR can lead to renin release from JG cells.
Reason R: JGA is a sensitive region formed at contact between DCT and afferent arteriole.
(1)Both A and R are true and R is the correct explanation of A.
(2)Both A and R are true but R is not the correct explanation of A.
(3)A is true but R is false.
(4)A is false but R is true.
112.Assertion A: PCT has high reabsorptive efficiency.
Reason R: It is lined by simple cuboidal brush-border epithelium that increases surface area.
(1)Both A and R are true and R is the correct explanation of A.
(2)Both A and R are true but R is not the correct explanation of A.
(3)A is true but R is false.
(4)A is false but R is true.
113.Assertion A: Filtrate becomes concentrated in the descending limb of Henle's loop.
Reason R: The descending limb is permeable to water but almost impermeable to electrolytes.
(1)Both A and R are true and R is the correct explanation of A.
(2)Both A and R are true but R is not the correct explanation of A.
(3)A is true but R is false.
(4)A is false but R is true.
114.Assertion A: Filtrate becomes diluted while moving upward in the ascending limb.
Reason R: Ascending limb is impermeable to water but allows electrolyte transport.
(1)Both A and R are true and R is the correct explanation of A.
(2)Both A and R are true but R is not the correct explanation of A.
(3)A is true but R is false.
(4)A is false but R is true.
115.Assertion A: Medullary interstitium shows increasing osmolarity toward the inner medulla.
Reason R: Countercurrent arrangements involving Henle's loop and vasa recta help maintain the gradient.
(1)Both A and R are true and R is the correct explanation of A.
(2)Both A and R are true but R is not the correct explanation of A.
(3)A is true but R is false.
(4)A is false but R is true.
116.Assertion A: ADH prevents diuresis.
Reason R: ADH facilitates water reabsorption from latter parts of the tubule.
(1)Both A and R are true and R is the correct explanation of A.
(2)Both A and R are true but R is not the correct explanation of A.
(3)A is true but R is false.
(4)A is false but R is true.
117.Assertion A: Angiotensin II increases GFR.
Reason R: Angiotensin II is a powerful vasodilator that lowers glomerular blood pressure.
(1)Both A and R are true and R is the correct explanation of A.
(2)Both A and R are true but R is not the correct explanation of A.
(3)A is true but R is false.
(4)A is false but R is true.
118.Assertion A: ANF acts as a check on the renin-angiotensin mechanism.
Reason R: ANF causes vasodilation and decreases blood pressure.
(1)Both A and R are true and R is the correct explanation of A.
(2)Both A and R are true but R is not the correct explanation of A.
(3)A is true but R is false.
(4)A is false but R is true.
119.Assertion A: Micturition involves relaxation of the urethral sphincter.
Reason R: CNS motor messages initiate bladder smooth muscle contraction and sphincter relaxation.
(1)Both A and R are true and R is the correct explanation of A.
(2)Both A and R are true but R is not the correct explanation of A.
(3)A is true but R is false.
(4)A is false but R is true.
120.Assertion A: Dialysing fluid can clear nitrogenous wastes from blood.
Reason R: Dialysing fluid has the same composition as plasma including nitrogenous wastes.
(1)Both A and R are true and R is the correct explanation of A.
(2)Both A and R are true but R is not the correct explanation of A.
(3)A is true but R is false.
(4)A is false but R is true.
121.In the diagram of a nephron showing afferent and efferent arterioles, which direction pairing is correct?
(1)Afferent arteriole brings blood to glomerulus; efferent arteriole carries it away
(2)Efferent arteriole brings blood; afferent arteriole carries it away
(3)Both arterioles carry filtrate from tubule to pelvis
(4)Afferent arteriole is the collecting duct; efferent arteriole is ureter
122.In a labelled renal corpuscle diagram, the structure enclosing the glomerular tuft is the:
(1)PCT
(2)Bowman's capsule
(3)vasa recta
(4)calyx
123.In the kidney longitudinal section, medullary pyramids project into:
(1)calyces
(2)glomeruli
(3)ureters directly
(4)Bowman's capsules
124.If a diagram shows a notch on the inner concave side of kidney where ureter and vessels enter, that label is:
(1)renal column
(2)hilum
(3)podocyte
(4)vasa recta
125.In the countercurrent diagram, the osmolarity should generally change from cortex to inner medulla as:
(1)1200 → 300 mOsmol/L
(2)300 → 1200 mOsmol/L
(3)125 → 180 mOsmol/L
(4)1.5 → 25 mOsmol/L
126.A student labels the descending limb as 'impermeable to water and dilutes filtrate'. What is the error?
(1)It should be permeable to water and concentrates filtrate downward
(2)It should be the DCT and should secrete bile
(3)It should be the renal pelvis and store urine
(4)It should be the vasa recta and release ANF
127.In a process-flow diagram of RAAS, the blank after renin acting on angiotensinogen should be:
(1)ANF
(2)angiotensin I followed by angiotensin II
(3)ADH followed by vasopressin
(4)anti-heparin followed by heparin
128.In a micturition reflex flow chart, the correct order is:
(1)Bladder stretch → CNS signal → bladder contraction + sphincter relaxation → urine release
(2)CNS signal → urea conversion → bladder stretch → filtration
(3)Bladder stretch → sphincter contraction → glomerular filtration → urine release
(4)ADH release → bladder contraction → renin release → urine release
129.In a hemodialysis flow chart, which step should occur before blood enters the dialysing unit?
(1)addition of heparin
(2)addition of anti-heparin
(3)release of ANF
(4)formation of renal calculi
130.In a dialysis unit diagram, the dialysing fluid should be shown as:
(1)plasma-like fluid without nitrogenous wastes
(2)pure water with high urea concentration
(3)bile containing bilirubin and biliverdin
(4)urine with glucose and ketone bodies
131.In a nephron diagram, the collecting duct should be shown extending:
(1)from cortex to inner medulla
(2)only from hilum to ureter
(3)from urethra to bladder
(4)only around the glomerulus
132.A diagram-based question shows urea entering the medullary interstitium from the collecting tubule. Which function does this support?
(1)maintaining osmolarity for urine concentration
(2)decreasing renal pelvis size
(3)forming filtration slits
(4)triggering ANF release
133.Choose the option with only correctly matched pairs.
A. Ammonia — most toxic, needs large water
B. Uric acid — least toxic, minimum water loss
C. Urea — pellet/paste excretion in reptiles
D. Ammonotelism — excretion of ammonia
(1)A, B and D only
(2)A and C only
(3)B, C and D only
(4)A, B, C and D
134.Choose the option containing only statements that are true for kidney anatomy.
A. Hilum is on inner concave surface.
B. Renal pelvis is funnel-shaped and has calyces.
C. Capsule is the outer tough layer.
D. Cortex is inner and medulla is outer.
(1)A, B and C only
(2)A and D only
(3)B, C and D only
(4)A, B, C and D
135.Choose the fully correct set of nephron statements.
A. Afferent arteriole forms glomerulus.
B. Efferent arteriole carries blood away.
C. Renal corpuscle includes DCT and collecting duct.
D. Vasa recta is U-shaped and parallels Henle's loop.
(1)A, B and D only
(2)A and C only
(3)B, C and D only
(4)A, B, C and D
136.Choose the set with only correctly placed nephron segment functions.
A. PCT — nearly all essential nutrients and 70–80% electrolytes/water reabsorbed
B. Descending limb — water permeable, electrolyte nearly impermeable
C. Ascending limb — water impermeable, electrolyte transport
D. DCT — no role in pH or ion balance
(1)A, B and C only
(2)A and D only
(3)B, C and D only
(4)A, B, C and D
137.Choose the correct regulatory chain(s).
A. Fluid loss → ADH → water reabsorption
B. Fall in GFR → renin → angiotensin II → vasoconstriction
C. Increased atrial blood flow → ANF → vasodilation
D. Increased body-fluid volume → more ADH release
(1)A, B and C only
(2)A and D only
(3)B, C and D only
(4)A, B, C and D
138.Choose the option with all correct clinical associations.
A. Glycosuria — glucose in urine
B. Ketonuria — ketone bodies in urine
C. Uremia — urea accumulation in blood
D. Renal calculi — crystallised salt mass in kidney
(1)A, B, C and D
(2)A, B and C only
(3)A, C and D only
(4)B, C and D only
139.Choose the option with only correct dialysis-related statements.
A. Blood is taken from an artery.
B. Heparin is added before the dialysing unit.
C. Dialysing fluid lacks nitrogenous wastes.
D. Cleared blood returns through a vein after anti-heparin.
(1)A, B, C and D
(2)A, B and C only
(3)A, C and D only
(4)B, C and D only
140.A desert reptile must conserve water while removing nitrogenous waste. Based on the chapter, the most suitable waste form is:
(1)ammonia dissolved and diffused across gills
(2)uric acid excreted as pellet or paste
(3)urea retained in large volume of urine
(4)ammonium ions removed primarily by kidney filtration
141.If a patient's ADH release is strongly suppressed due to increased body-fluid volume, the immediate renal tendency would be:
(1)less water reabsorption in latter tubule parts and more diuresis
(2)more renin release by JG cells due to atrial stretch
(3)more water reabsorption due to aldosterone being ANF
(4)complete absence of glomerular filtration
142.A mutation damages brush border formation in PCT cells. Which function would be most directly affected based on the chapter?
(1)surface area for reabsorption in PCT
(2)release of ANF from atria
(3)formation of urinary bladder stretch receptors
(4)sebum secretion through sebaceous glands
143.If vasa recta were absent or highly reduced, the nephron type most consistent with that observation would be:
(1)juxtamedullary nephron
(2)cortical nephron
(3)malpighian tubule
(4)renal pelvis
144.A dialysing fluid accidentally contains high urea concentration. Based on the chapter's principle, urea removal from blood would be reduced because:
(1)movement depends on concentration gradient and wastes should be absent from dialysing fluid
(2)cellophane membrane moves only proteins, not urea
(3)heparin converts urea into glucose
(4)anti-heparin must be added before dialysis begins
145.A student says, 'High urine concentration is produced mainly by liver bile pigments in the medulla.' What is the best correction?
(1)The medullary gradient is mainly due to NaCl and urea maintained by Henle's loop and vasa recta.
(2)The liver directly produces vasa recta to concentrate urine.
(3)Bile pigments form filtration slits in Bowman's capsule.
(4)Urine concentration depends only on urinary bladder stretch.
146.A patient has inflammation of glomeruli. Which named condition from the chapter fits best?
(1)renal calculi
(2)glomerulonephritis
(3)glycosuria
(4)ketonuria
147.Which statement correctly uses the chapter's opening idea on excretion?
(1)Only nitrogenous wastes accumulate in animals and all are removed completely.
(2)Animals may accumulate nitrogenous wastes, CO2, water and ions, and these substances may need total or partial removal.
(3)Excretion is limited to removal of excess food from the digestive tract.
(4)The chapter excludes nitrogenous wastes and focuses only on salts.
148.Which combined statement is correct?
A. Some urea may be retained in kidney matrix to maintain desired osmolarity.
B. Henle's loop plays a significant role in maintaining high osmolarity of medullary interstitial fluid.
C. Mammals can produce concentrated urine.
D. Urea retention always means kidney failure.
(1)A, B and C only
(2)A and D only
(3)B, C and D only
(4)A, B, C and D
149.Which option best combines kidney position and adult kidney size?
(1)Between last thoracic and third lumbar vertebrae; 10–12 cm long, 5–7 cm wide, 2–3 cm thick and 120–170 g
(2)Between cervical vertebrae; 5–7 cm long and 10–12 g
(3)Inside urinary bladder; 2–3 cm long and 1200–1700 g
(4)In renal pelvis; 120–170 cm long and 5–7 g
150.Which set contains only extra excretory points stated in the chapter?
(1)Sweat and sebaceous glands eliminate some substances; saliva may eliminate small nitrogenous wastes; transplant uses a close relative donor preferably to reduce rejection
(2)Sweat removes all urea; saliva forms glomeruli; transplant donors should be unrelated to maximize rejection
(3)Sebum contains glucose and amino acids; saliva causes micturition; transplant is first step for every urine abnormality
(4)Liver releases ANF; sweat releases renin; saliva releases aldosterone

Answer Key

11
22
33
42
52
62
72
81
92
102
113
122
131
143
152
162
172
181
192
202
211
224
231
242
252
262
273
284
291
302
311
322
331
341
351
361
371
381
391
401
411
421
431
441
451
461
471
481
491
501
511
521
531
541
551
561
571
581
591
601
611
621
631
641
654
664
674
683
694
703
714
724
734
744
754
764
774
784
794
804
814
824
834
844
854
864
874
881
891
901
911
921
931
941
951
961
971
981
991
1001
1011
1021
1031
1041
1051
1061
1074
1081
1091
1101
1112
1121
1131
1141
1151
1161
1173
1181
1191
1203
1211
1222
1231
1242
1252
1261
1272
1281
1291
1301
1311
1321
1331
1341
1351
1361
1371
1381
1391
1402
1411
1421
1432
1441
1451
1462
1472
1481
1491
1501